Mood disorders in children, adolescents, and adults are complex and often influenced by biology, genetics, lifestyle, and medical factors. While antidepressant medications such as SSRIs and SNRIs are commonly prescribed, some patients experience only partial relief. In these cases, targeted nutritional support may play a valuable role. DeplinPRO Mood Health™ is a prescription medical food designed to support neurotransmitter synthesis and overall mood regulation when used under medical supervision.
At Dr. Priti Kothari’s psychiatric practice in Boca Raton, DeplinPRO may be considered as part of a comprehensive, individualized treatment plan for eligible patients.
What Is DeplinPRO Mood Health?
DeplinPRO Mood Health™ is a prescription medical food formulated with L-methylfolate, the active form of folate that the brain can directly use. Unlike standard folic acid supplements, L-methylfolate does not require multiple metabolic steps to become active, making it particularly helpful for individuals who have difficulty converting folate due to genetic or medical factors.
L-methylfolate plays a key role in the production of neurotransmitters such as serotonin, dopamine, and norepinephrine, which are essential for mood regulation.
Who Can Benefit From DeplinPRO Mood Health?
DeplinPRO Mood Health™ can be used in adults and adolescents aged 12 years and older with mood disorders, under the guidance of a qualified psychiatrist. Patients who may benefit the most often have specific clinical or lifestyle characteristics.
Partial Response to Antidepressants
Some individuals taking SSRIs or SNRIs experience incomplete symptom improvement. DeplinPRO is intended to be used alongside antidepressant therapy, not as a replacement, to help enhance treatment response.
Medical Conditions That Affect Nutrient Absorption
Patients with certain medical conditions may have impaired folate metabolism or absorption, including:
- Diabetes
- Gastrointestinal disorders
- Chronic kidney or liver disease
Genetic Variations
Certain genetic polymorphisms can affect how the body processes folate and vitamin D. These include variations in genes such as:
- MTHFR
- DHCR7
- CYP2R1 and CYP24A1
- SLC39A4
Individuals with these variations may benefit from bioavailable nutritional support like L-methylfolate.
Lifestyle and Environmental Factors
Modern lifestyles can also impact mood and nutrient levels. DeplinPRO may be considered for patients with:
- Elevated inflammatory markers (such as hsCRP)
- High stress levels
- Alcohol or tobacco use
- Limited sunlight exposure
- Overweight or obesity (BMI ≥ 30)
Preference for a Holistic Treatment Approach
Some patients and families prefer incorporating nutritional and holistic strategies into their mental health care. DeplinPRO aligns well with an integrative psychiatric approach when medically appropriate.
Recommended Use and Safety Considerations
How Is DeplinPRO Taken?
- Dosage: Typically 1 capsule once daily (QD)
- Age: Approved for patients aged 12 years and older
- Use: Intended to be used under medical supervision
- Combination therapy: Designed to be used with an antidepressant, not as monotherapy
Because DeplinPRO is a prescription medical food, it should only be used after evaluation by a qualified psychiatrist who can determine appropriateness based on medical history, current medications, and overall mental health needs.
DeplinPRO Mood Health in Child and Adolescent Psychiatry
In child and adolescent psychiatry, careful attention is paid to brain development, nutritional needs, and medication safety. For teens aged 12 and older who struggle with depression or mood-related symptoms, DeplinPRO may offer additional support when standard treatments are not fully effective.
At our Boca Raton psychiatric practice, treatment decisions are always individualized and family-centered, ensuring that both clinical evidence and patient comfort are prioritized.
About Dr. Priti Kothari, Psychiatrist in Boca Raton
Dr. Priti Kothari is a board-certified child, adolescent, and adult psychiatrist, as well as a pediatric psychiatrist, seeing patients from age 1 through adulthood. She completed her fellowship training at Johns Hopkins Medical Center and earned her undergraduate degree from Princeton University, where she majored in Anthropology with a concentration in Women’s Studies.
Dr. Kothari is known for her compassionate, evidence-based approach and her ability to integrate medical, psychological, and lifestyle factors into personalized treatment plans. Her Boca Raton practice emphasizes comprehensive psychiatric care, including therapy, medication management, and thoughtful use of adjunctive treatments such as nutritional support.
FAQs About DeplinPRO Mood Health
Is DeplinPRO the same as a regular vitamin supplement?
No. DeplinPRO is a prescription medical food, not an over-the-counter vitamin. It contains a specific, therapeutic form of folate designed to support neurotransmitter synthesis in patients with mood disorders.
Can DeplinPRO replace antidepressant medication?
No. DeplinPRO is intended to be used in combination with antidepressants, not as a substitute. Any changes to medication should only be made under psychiatric supervision.
Is DeplinPRO safe for teenagers?
DeplinPRO is approved for adolescents aged 12 years and older when prescribed and monitored by a psychiatrist.
How long does it take to see results?
Response times vary. Some patients may notice improvements within several weeks, while others may require longer-term use as part of a comprehensive treatment plan.
Do I need genetic testing to use DeplinPRO?
Genetic testing is not required, but it may be helpful in certain cases. Your psychiatrist can determine whether testing is appropriate.
Final Thoughts
DeplinPRO Mood Health™ represents a science-backed nutritional option that may help support mood regulation in patients with specific biological, genetic, or lifestyle factors. When prescribed thoughtfully, it can be a valuable adjunct to traditional psychiatric care.
If you are seeking a psychiatrist in Boca Raton who offers comprehensive, integrative mental health treatment for children, adolescents, and adults, Dr. Priti Kothari provides expert, compassionate care tailored to each patient’s unique needs.
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